NAD+ nasal spray
A needle-free option.
NAD+ nasal spray is a compounded NAD+ preparation, prescription required, sprayed into the nose instead of injected. It is not FDA-approved. Your pharmacy label gives the number of sprays, and your provider sets the dose. From $149 per 4 weeks on the 52-week plan ($1,937 for 13 fills) · $179 on 12 weeks ($537) · $229 month-to-month.
$149per 4 weeks on the 52-week plan ($1,937 for 13 fills)
Opens the NAD+ application on OpenLoop, in English. Our care team can help in English or Spanish.
Why REMEVi for NAD+
- One price at every doseFrom $149 per 4 weeks on the 52-week plan. Your dose can change; your plan price does not.
- Prescribed by a licensed providerA licensed provider reviews your health history online and decides whether NAD+ fits you.
- Three formsInjection, nasal spray or oral dropper, at the same plan prices.
- Ships to your doorPrepared by a licensed pharmacy. Median 3.6 days from payment to shipment.
- Care in English or SpanishOur care team answers in your language, before and after you start.
How NAD+ nasal spray is used
A nasal preparation is used at home on the schedule your provider prescribes. These are the usual steps for a nasal spray pump; your pharmacy’s instructions come first wherever they differ.
- Read your pharmacy label first: it gives the number of sprays, how often and how to store the bottle. It overrides any general steps here.
- Before the first use, prime the pump by spraying into the air until a fine mist comes out, as the label directs.
- Blow your nose gently. Tilt your head slightly forward and place the tip just inside one nostril.
- Spray while breathing in gently through the nose, then repeat in the other nostril if your label says so.
- Wipe the tip, replace the cap and store the bottle as labeled. Some pharmacies label NAD+ nasal spray for the refrigerator.
NAD+ nasal spray vs injection
The two forms differ in how they are given; neither has been shown to work better. This table does not rank them.
| Attribute | Nasal spray | Injection |
|---|---|---|
| Needle | No | Yes, a small needle under the skin |
| How it’s given | Sprayed into the nose, as the pharmacy label directs | Injected into the fatty tissue under the skin, as prescribed |
| What the research covers | Animal studies of intranasal NAD+ delivery; no human absorption study found | Human NAD+ research is mostly on IV infusions and oral precursors; no trial of at-home subcutaneous NAD+ found |
| Commonly reported effects | Nasal irritation, a brief burning feeling, headache, tiredness | Redness or tenderness where you inject, flushing, nausea |
| Price | Same plans: from $149 per 4 weeks (52-week plan) | Same plans: from $149 per 4 weeks (52-week plan) |
In a 2007 rat study, NAD+ given through the nose raised NAD+ levels in the brain. That is animal research. We found no human study measuring how much NAD+ the body absorbs from a nasal spray, so the nasal form should not be expected to match an injection or an IV infusion. Intranasal NAD+ in rats (Ying et al., 2007)
NAD+ nasal spray side effects
Published patient instructions for NAD+ nasal sprays list mild nasal irritation, a brief burning feeling, headache and tiredness as the most common effects, with dizziness, nausea or shortness of breath less often. Stop and contact your care team if an effect is severe or does not ease, and seek urgent care for trouble breathing.
Ingredient quality matters
FDA has warned that food-grade NAD+ is not suitable for sterile compounding and has received reports of severe chills, shaking, vomiting and fatigue after injectable NAD+. That alert is about injectable products and ingredient sourcing, not about REMEVi specifically; it is one reason a licensed pharmacy and prescriber matter for every form.
FDA: ingredient quality and injectable NAD+ · NAD+ side effects by route · Are NAD+ injections safe?
NAD+ nasal spray cost
From $149 per 4 weeks on the 52-week plan ($1,937 for 13 fills)
REMEVi NAD+ plans (USD). Same price at every dose and every renewal of your plan.
| Plan | Per 4 weeks | Charged |
|---|---|---|
| 52 weeks (13 fills) | $149 | $1,937 for 52 weeks (13 four-week fills) |
| 12 weeks | $179 | $537 for 12 weeks (3 four-week fills) |
| Month-to-month | $229 | $229 every 4 weeks, month-to-month |
Injection, nasal spray or oral dropper: the same plan prices. A four-week fill is 28 days, not a calendar month. Shown at checkout as the 3-month and 13-month plans.
Opens the NAD+ application on OpenLoop, in English. Our care team can help in English or Spanish.
NAD+ nasal spray questions
What is NAD+ nasal spray used for?
It is a needle-free way to take prescribed NAD+, a coenzyme your cells use to make energy. People explore it for cellular wellness, but research has not shown that NAD+ nasal spray improves energy, focus or aging in people. A licensed provider decides whether it fits your goals and health history.
How many sprays of NAD+ should I use?
Use exactly what your pharmacy label and prescription say. Strength differs between compounded preparations, so a spray count from another product or a website may not match yours. Your provider sets the dose and can adjust it; ask your care team before changing how much or how often you spray.
Is NAD+ nasal spray better than injections?
Neither form has been shown to work better. The nasal spray avoids needles; the injection is the form published home dosing protocols usually describe. Absorption through the nose has been studied in animals, not measured in people. Your provider helps you choose based on your preferences and health history, and both have the same plan prices.
What are the side effects of NAD+ nasal spray?
Published patient instructions for NAD+ nasal sprays list mild nasal irritation, a brief burning feeling, headache and tiredness as the most common effects, with dizziness, nausea or shortness of breath less often. Stop and contact your care team if an effect is severe or does not ease, and seek urgent care for trouble breathing.
Do I need a prescription for NAD+ nasal spray?
Yes, at REMEVi. The nasal spray is a compounded preparation made by a licensed pharmacy under a prescription from a licensed provider, after a review of your health history in the online application. It is not the same product as over-the-counter NAD+ supplements or precursor capsules.
How much does NAD+ nasal spray cost?
From $149 per 4 weeks on the 52-week plan ($1,937 for 13 fills) · $179 on 12 weeks ($537) · $229 month-to-month. The nasal spray, the injection and the oral dropper have the same plan prices, and each plan has one price at every dose and every renewal.
Prefer no needles?
Ask about the nasal spray.
From $149 per 4 weeks on the 52-week plan ($1,937 for 13 fills) · $179 on 12 weeks ($537) · $229 month-to-month.
Find my NAD+ planOpens the NAD+ application on OpenLoop, in English. Our care team can help in English or Spanish.
Not prescribed? Full refund.Medically reviewed by Linda West-Conforti, RN · CA RN #389453 ·