Published subcutaneous NAD+ protocols commonly list about 20 to 100 mg per injection, one to three times a week, starting low. Compounded NAD+ is not FDA-approved, and your licensed provider sets your dose, form and schedule. Below: what two pharmacy protocols list, and how and where to inject NAD+ at home.
What published pharmacy protocols list — your provider sets your dose; never self-dose.
| Source (read 2026-09-29) | Subcutaneous dose per injection | Frequency | How the protocol starts |
|---|---|---|---|
| MediVera Compounding Pharmacy | 20–100 mg | 1–3 times a week | Start low, increase by 20 mg every 1–2 weeks |
| Empower Pharmacy | About 20 mg, up to about 100 mg; many protocols use 50–100 mg | 1–3 times a week (“a few times per week”) | Start at the lower end and work up if tolerated |
Other pharmacies and clinics publish their own schedules, some with a short daily “loading” phase. Forms, plans and how care works are on the NAD+ injections page.
NAD+ is a coenzyme prescribed as a compounded medication by a licensed provider after an individual evaluation. Because it’s a prescription, dosing is set per patient — shaped by:
Your provider weighs all of these when setting your dose.
While specifics are always provider-set, a few general points come up:
NAD+ given too quickly is associated with temporary, uncomfortable effects — flushing, nausea, or a feeling of pressure — that ease when the pace is slowed. That’s exactly why providers commonly start conservatively and why NAD+ is prescribed and supervised rather than self-managed. (More in NAD+ injection side effects.)
Follow your pharmacy’s instructions and the technique your care team shows you; they come first wherever they differ from these general steps. A subcutaneous injection generally goes like this:
Brief redness, tenderness or a burning feeling at the site can happen. Tell your care team about any reaction that is severe or does not ease.
NAD+ injections go into the fatty tissue just under the skin. MedlinePlus lists these subcutaneous sites:
Rotate sites: move each injection at least 1 inch from the last one to keep your skin healthy. Source: MedlinePlus, subcutaneous (SQ) injections, read 2026-09-29
Dispose of needles safely: put used needles and syringes in a sharps disposal container right away. Never put loose needles in household or public trash or recycling, and never flush them. If you don’t have an FDA-cleared container, a heavy-duty plastic household container, such as a laundry detergent bottle, can be used. Source: FDA, Safely Using Sharps at Home, read 2026-09-29
Start with a licensed provider who reviews your history and, if NAD+ fits, sets your dose, form and schedule. See how REMEVi sources NAD+: a licensed 503A compounding pharmacy, on your prescription.
Ready to talk to a provider? REMEVi prescribes NAD+ online — one plan price at every dose, bilingual care, with a licensed US provider setting your dosing and a structured schedule. See the plans on NAD+ injection cost.
Related reading: NAD+ injections vs IV therapy and NAD+ injection benefits.
This article is for general education and is not medical advice.
FDA has received reports of severe chills, shaking, vomiting and fatigue after NAD+ injectable medicines, with some patients requiring medical care. It warns that food-grade ingredients are unsuitable for sterile compounding. Those reports do not establish a risk frequency for a particular preparation. Source: FDA: ingredients for sterile compounding
Published subcutaneous protocols commonly list about 20 to 100 mg per injection, given one to three times a week, often starting near the low end. Your licensed provider sets your own dose and schedule based on your history and how you tolerate it.
Most published subcutaneous protocols are not daily: they list injections one to three times a week. Some clinics publish short daily loading schedules at higher amounts, and these differ widely. There is no established daily NAD+ dose, so follow the schedule on your own prescription.
Frequency is provider-determined. Published protocols range from one to three injections a week, sometimes more often at the start and then spaced out for maintenance. Your provider decides the schedule for you and may adjust it over time based on how you tolerate it.
It depends on your preparation's concentration and your prescribed dose. Published protocols list roughly 20 to 100 mg per injection, but the volume you draw up depends on the strength on your pharmacy label. Confirm the milligrams and the syringe markings with your pharmacy; never convert a dose from another product.
NAD+ administered too quickly can cause temporary effects like flushing, nausea, or a feeling of pressure, so providers often start conservatively and adjust. Going slow is a comfort-and-tolerance measure, which is one reason NAD+ is prescribed and supervised rather than self-dosed.
There is no FDA-approved NAD+ dose, and we found no peer-reviewed trial of at-home subcutaneous dosing, so each pharmacy or clinic publishes its own protocol. Charts differ in starting dose, how fast they increase and how often they inject. That is why a chart cannot replace a provider who knows your history.
NAD+ injections go into the fatty tissue under the skin. Common subcutaneous sites are the belly at least 2 inches from the navel, the outer upper thigh and the back or side of the upper arm. Rotate sites at least 1 inch apart and follow your pharmacy's instructions.
Yes — different delivery forms are dosed differently, and your provider accounts for that when prescribing. REMEVi offers NAD+ as an injection, nasal spray, or oral dropper, and the provider matches both the form and the dosing to your situation.
Licensed US providers, transparent pricing, and medication shipped to your door. See the plans and start when you are ready.
See NAD+ injection plans